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例1男,82岁,因淋巴结炎于2002年7月18日来我院治疗,既往无药物过敏史。给予盐酸左氧氟沙星(爱兴)200ml(0.2g)静滴,bid。当日输液时患者无明显不适,第2天上午9时第2次输液。输液开始2min左右,患者突然出现头晕、大汗、乏力、憋喘,并有一过性意识障碍。查体:T 36.5℃,P 60次·min~(-1),R 30次·min~(-1),BP 60/40mmHg。立即停药,吸氧、心电监护;开放两路输液通路:一路给予静滴 0.9％氯化钠注射液250ml,另一路给予 0.9％氯化钠注射注 250ml+地塞米松 10mg入壶静滴;同时给予肾上腺素 0.5mg皮下注射。15min后患者血压回升至 95/70mmHg,30min后血压 110/70mmHg。7月21日患者仍感胸闷、气短。查体:T 38.5℃,BP 120/80mmHg,P 80次·min~(-1),给予5％葡萄糖注射液500ml+丹参注射液30ml静滴,柴胡注射注 4ml,im,5％葡萄糖氯化钠注射液 500ml+清开灵 30ml静滴。7月23日,患者 T 37.2℃,BP 120/80mmHg,P 80次·min~(-1),症状消失。
Example 1 Male, 82 years old, came to our hospital for treatment of lymphadenitis on July 18, 2002. There was no previous history of drug allergy. Give levofloxacin hydrochloride (love Xing) 200ml (0.2g) intravenous infusion, bid. The patient had no significant discomfort on the day of infusion, and the second infusion at 9 am on the second day. Infusion 2min or so, the patient suddenly dizziness, sweating, fatigue, wheezing, and a transient disturbance of consciousness. Examination: T 36.5 ℃, P 60 times · min -1, R 30 times · min -1, BP 60/40 mmHg. Immediate withdrawal, oxygen, ECG monitoring; Open the two infusion channels: all the way to intravenous 0.9% sodium chloride injection 250ml, the other way to give 0.9% sodium chloride injection note 250ml + dexamethasone 10mg into the pit intravenous infusion; At the same time give epinephrine 0.5mg subcutaneous injection. After 15min, the patient’s blood pressure rose to 95/70 mmHg, and blood pressure was 110/70 mmHg after 30 minutes. July 21 patients still feel chest tightness, shortness of breath. Examination: T 38.5 ℃, BP 120 / 80mmHg, P 80 times · min -1, given 5% glucose injection 500ml + Salvia injection 30ml intravenous injection, Bupleurum injection injection 4ml, im, 5% glucose chloride Sodium injection 500ml + Qing Kai Ling 30ml intravenous infusion. July 23, the patient T 37.2 ℃, BP 120 / 80mmHg, P 80 times · min -1, the symptoms disappeared.