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目的 :探讨破伤风的发病和死亡机理及临床药物应用的方法。方法 :综合分析 2 38例病人在病因及毒理学方面的变化 ,进一步指导临床治疗及预后。结果 :喉痉挛及呼吸衰竭是死亡的主要原因 ,抗毒素、镇静剂的合理应用及密切观察病情为治疗提供了保障。结论 :及时而全面的综合疗才能有效地降低该病的死亡率。
Objective: To investigate the pathogenesis and death mechanism of tetanus and the clinical application of the drug. Methods: A comprehensive analysis of 238 cases of patients in the etiology and toxicology changes, to further guide the clinical treatment and prognosis. Results: Laryngeal spasm and respiratory failure were the main causes of death. The rational use of anti-toxins and sedatives and close observation of the disease provided the guarantee for the treatment. Conclusion: A timely and comprehensive combination therapy can effectively reduce the mortality of the disease.