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本文就中药新药研制中有关药理学应用基础研究的几个命题进行了分析探讨。主要有 :药效评价的方法学、复方药代研究的方法学、证动物模型方法以及对药效靶器官毒理学研究等。并提出了相应的对策。上述应用基础研究的命题主要是在当前中药新药研制中所面临而亟待解决的问题。对这些问题的研讨 ,将有助于推动中药新药研究以及其水平的提高
This article analyzes and discusses several propositions concerning pharmacology application basic research in the development of new Chinese medicines. The main ones are: Methodology for efficacy evaluation, Methodology for compound pharmacokinetics, Animal model method for identification, and Toxicological studies on target efficacy of drugs. And put forward the corresponding countermeasures. The above-mentioned propositions for basic research in application are mainly problems that are urgently needed to be solved in the development of new traditional Chinese medicines. The discussion of these issues will help promote the study of new Chinese medicines and their improvement