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研究人员进行一项前瞻性研究,观察妇科病人施行大手术前服用固定小剂量苄丙酮香豆素(每天1mg)是否能预防其深部静脉血栓形成。104名病人随机分为3组:固定小剂量苄丙酮香豆素组;足量口服抗疑剂组;非治疗(对照)组。结果发现,前两组病人的深静脉血栓形成发病率(分别为9％(3/32)及3％(1/35)〕比对照组〔30％(11/37)〕明显降低,但抗凝剂治疗的两组病人无明显差异。手术时第一组病人的凝血酶
The researchers conducted a prospective study to determine whether prescribing fixed-dose warfarin (1 mg daily) before major surgery in gynecologic patients prevented deep venous thrombosis. 104 patients were randomly divided into 3 groups: fixed-dose warfarin group; sufficient oral anti-suspicious agent group; non-treatment (control) group. The incidence of deep venous thrombosis was significantly lower in the first two groups (9% (3/32) and 3% (1/35), respectively) than in the control group (30% (11/37) There was no significant difference between the two groups of patients treated with coagulant, the first group of patients with thrombin at the time of surgery