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目的观察步长稳心颗粒与酒石酸美托洛尔联合治疗冠心病心律失常的效果。方法将2008年3月至2009年10月门诊及住院治疗的75例冠心病心律失常患者,随机分为两组,治疗组,给予步长稳心颗粒9 g 3次/d口服,酒石酸美托洛尔20~80 mg 2次/d口服。对照组,单纯口服酒石酸美托洛尔,20~80 mg 2次/d口服。分别观察治疗前后临床症状改善情况,心电图,24 h动态心电图心律失常改善情况。结果在临床症状改善方面,治疗组总有效率为92.5%,对照组总有效率为73.3%,治疗组明显高于对照组(P<0.01)。心电图,动态心电图的改善方面,两组比较差异无显著性(P>0.05)。结论步长稳心颗粒与酒石酸美托洛尔联合治疗冠心病心律失常临床疗效显著,不良反应少见,值得进一步推广。
Objective To observe the effect of Wenxin granule and metoprolol tartrate in the treatment of arrhythmia of coronary heart disease. Methods From March 2008 to October 2009, 75 outpatients and hospitalized patients with coronary heart disease and arrhythmia were randomly divided into two groups. The patients in the treatment group received Stephensing Granule 9 g 3 times / d orally, Lol 20 ~ 80 mg 2 times / d orally. Control group, oral pure oral metoprolol tartrate, 20 ~ 80 mg 2 times / d orally. Clinical symptoms were observed before and after treatment to improve the situation, ECG, 24 h improvement of arrhythmia. Results In clinical symptom improvement, the total effective rate was 92.5% in the treatment group and 73.3% in the control group, which was significantly higher in the treatment group than in the control group (P <0.01). There was no significant difference between the two groups in the improvement of ECG and Holter (P> 0.05). Conclusion The step-stabilizing granule and metoprolol tartrate combined treatment of coronary heart disease arrhythmia significant clinical effect, rare adverse reactions, it is worth further promotion.