百日咳感染及百日咳全菌体和无细胞菌苗免疫后人体对百日咳毒素的IgG应答

来源 :国外医学.预防.诊断.治疗用生物制品分册 | 被引量 : 0次 | 上传用户:cxsxj
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作者从46名观察对象的184份血清样品中测定抗百日咳毒素(PT)的IgE水平.将观察对象分成3组.第1组包括23例百日咳患者(其中10例是未曾免疫的平均年龄为2.5周岁的儿童)、13名成人和经3针DTP接种的大龄儿童.于观察之初和6周后采血.第2组有15名6月龄免疫幼儿,经3次皮下接种,每次0.5ml,间隔4周,其中5人接种百日咳全菌体菌苗,10人接种百日咳无细 The authors determined IgE levels of pertussis toxin (PT) in 184 serum samples from 46 subjects.The subjects were divided into three groups: Group 1 consisted of 23 patients with pertussis (10 of whom were non-immunized with an average age of 2.5 Year-old children), 13 adults and older children vaccinated with 3-dose DTP. Blood samples were taken at the beginning of the observation period and after 6 weeks. In the second group, 15 children aged 6 months were immunized subcutaneously with 0.5 ml , 4 weeks apart, of which 5 were inoculated with whole-cell bacteremia vaccine, 10 were not vaccinated whooping cough
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