论文部分内容阅读
目的探讨肾病患者高尿酸血症与脂质代谢紊乱的相关性。方法将2012年2月-2013年2月来我院320例高尿酸血症患者分为慢性肾病高尿酸组(高尿酸组)与慢性肾病尿酸正常组(正常组),选择同期尿酸正常体检者100例为对照组,比较三组间TG、TC、LDL-C、HDL-C及BMI水平及发病率。结果三组比较,TG、TC、LDL-C、HDL-C及BMI组间差异均具有统计学意义(P<0.05);三组间两两比较,TG、TC、LDL-C及BMI差异具有统计学意义(P<0.05),HDL-C差异无统计学意义(P>0.05)。结论高尿酸血症与肾功能损害、肥胖及脂代谢紊乱均密切相关,临床应重视尿酸水平的改变,并应避免慢性肾病、肥胖及高脂血症的发生。
Objective To investigate the correlation between hyperuricemia and dyslipidemia in patients with nephropathy. Methods 320 patients with hyperuricemia in our hospital from February 2012 to February 2013 were divided into chronic hyperuricemia group (hyperuricemia group) and chronic renal disease group (normal group), patients with normal uric acid 100 cases as control group, comparing the three groups of TG, TC, LDL-C, HDL-C and BMI levels and incidence. Results There was significant difference between TG, TC, LDL-C, HDL-C and BMI in the three groups (P <0.05). The differences of TG, TC, LDL-C and BMI among the three groups were statistically significant Statistical significance (P <0.05), HDL-C difference was not statistically significant (P> 0.05). Conclusions Hyperuricemia is closely related to the impairment of renal function, obesity and lipid metabolism. The clinic should pay attention to the change of uric acid level and should avoid the occurrence of chronic kidney disease, obesity and hyperlipidemia.