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勾了探讨用组织中乳酸和次黄嘌呤的变化作为急性缺氧的辅助诊断指标,我们将16只大耳白毛家兔随机分为二组:低压舱组以30 m/s的速度上升至8000 m,停留30 min后迅速降至地面;对照组地面放置30 min。动物断头处死后。立即取其脑、心、肾、肝、肌肉组织,制做组织匀浆,测试组织中乳酸及次黄嘌呤含量。结果急性缺氧组组织乳酸含量较对照组明显升高;除心肌外,其他组织的次黄瞟呤含量均较对照组明显增高。表明大耳白毛家兔的组织乳酸、次黄嘌呤含量可作为判断急性缺氧的客观指标。
In order to explore the changes of lactic acid and hypoxanthine in tissues as an auxiliary diagnostic indicator for acute hypoxia, we divided 16 white-bellied white rabbits into two groups randomly: low-pressure cabin group increased at 30 m / s to 8000 m, stay for 30 min and then quickly dropped to the ground; control group placed 30 min on the ground. After the animal is decapitated Immediately take the brain, heart, kidney, liver, muscle tissue, making tissue homogenate, test tissue lactate and hypoxanthine content. Results The content of lactic acid in acute hypoxia group was significantly higher than that in control group. The content of hypoxanthine in all tissues except myocardium was significantly higher than that in control group. The results showed that the content of lactic acid and hypoxanthine in the tissues of white-eared white rabbit could be used as an objective index to judge acute hypoxia.