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目的综合分析社区感染性疾病患者关于合理用药咨询情况,为提高社区患者合理应用抗感染药物的理念和开展相关的健康教育提供信息。方法分析2014年1月-2016年12月该中心合理用药咨询室的社区感染性疾病患者的咨询资料。结果接待咨询患者216例次,咨询者所患感染性疾病以呼吸道感染占首位(73.15%),咨询药物类目多见于抗菌药物(62.45%),咨询药物知识内容主要为药物疗效(21.10%)、药物不良反应(20.51%)、疗程(18.42%)。咨询发现患者治疗中出现的药物不良反应以皮疹(13.13%)、头晕痛(11.25%)和胃肠道反应(10.00%)比例较高。引起药物不良反应的药物以喹诺酮类(21.88%)、头孢菌素类(15.63%)和青霉素类(14.06%)频率较高。导致药物不良反应的原因以无适应证用药(15.79%)、用药剂量过大(13.16%)和联合用药不当(12.50%)为主要诱因。患者参加相关合理用药学习讲座的频率为17.59%,用药说明书参阅率为36.11%。结论社区感染性疾病患者存在诸多不合理应用抗感染药物现状和由此引起的诸多影响疾病预后的因素,积极开展社区合理用药相关的科普教育颇为重要。
Objective To comprehensively analyze the consultation of patients with community-acquired infectious diseases on rational drug use and to provide information for community patients on the concept of rational use of anti-infective drugs and related health education. Methods Analyze the consultation data of patients with community-acquired infectious diseases from January 2014 to December 2016 in the Center for Rational Drug Use. Results 216 patients were consulted, 73.3% of the respondents were infected with infectious diseases, 73.15% of them were consulted with infectious diseases, 62.45% of them were consulted, and 21.10% , Adverse drug reactions (20.51%), course of treatment (18.42%). Counseling found that patients treated with drug adverse reactions rash (13.13%), dizziness (11.25%) and gastrointestinal reactions (10.00%) a higher proportion. Quinolones (21.88%), cephalosporins (15.63%) and penicillins (14.06%) were the most frequently reported drugs that caused adverse drug reactions. The main causes of adverse drug reactions were without indications (15.79%), overdose (13.16%) and improper combination (12.50%). Patients to participate in the appropriate frequency of seminars on drug use was 17.59%, medication reference rate of 36.11%. Conclusion There are many irrational use of anti-infective drugs in community patients with infectious diseases and the many factors that affect the prognosis of the disease. It is of great importance to actively carry out popular science education in communities with rational drug use.