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目的:观察低分子肝素钙联合盐酸地尔硫卓片(商品名:合心爽)治疗慢性肺源性心脏病急性发作的临床疗效。方法:全部病例59例,随机分为2组,治疗组:在常规氧疗、抗感染、平喘等治疗的同时,加低分子肝素钙5000U,皮下注射,每12h1次,合心爽30mg,3次/d;对照组:常规治疗。全部患者7～10d为1个疗程。治疗前后分别检查血气分析,红细胞比容及肺动脉收缩压(PASP)。结果:治疗组临床疗效明显优于对照组。结论:低分子肝素钙联合合心爽可以有效降低血液黏度和肺动脉压力,改善肺功能,疗效确切。
Objective: To observe the clinical efficacy of low molecular weight heparin combined with diltiazem hydrochloride tablets (trade name: Hexin Shuang) in the treatment of acute episodes of chronic cor pulmonale. Methods: All 59 cases were randomly divided into two groups. In the treatment group, low-molecular-weight heparin 5000U was injected subcutaneously once every 12h, concomitantly with 30mg while routine oxygen therapy, anti-infective, 3 times / d; control group: conventional treatment. All patients 7 ~ 10d for a course of treatment. Blood gas analysis, hematocrit and pulmonary artery systolic pressure (PASP) were examined before and after treatment. Results: The clinical efficacy of the treatment group was significantly better than that of the control group. CONCLUSION: Low molecular weight heparin combined with XHX can effectively reduce blood viscosity and pulmonary artery pressure and improve lung function, with definite curative effect.