由于放化疗有导致淋巴细胞减少的副作用,因此传统观念认为,放化疗之后机体免疫功能低下,不宜随即实施肿瘤疫苗诱导主动免疫治疗。由于缺乏客观、精确的指标从体内实验去评判放化疗与肿瘤疫苗治疗的关系,这方面的研究成果一直寥寥无几。近年来,随着肿瘤学研究和免疫学技术的进步 Because of the side effects of chemoradiotherapy leading to lymphopenia, the traditional concept that the immune function after radiotherapy and chemotherapy is low, should not be immediately followed by the implementation of tumor vaccine-induced active immunotherapy. Due to the lack of objective and accurate indicators from in vivo experiments to evaluate the relationship between chemoradiation and cancer vaccine treatment, the research results in this area have been very few. In recent years, with oncology research and immunological technology advances