论文部分内容阅读
目的探讨雷贝拉唑联合伊托必利治疗反流性食管炎的临床疗效。方法 64例反流性食管炎患者随机分成两组治疗组34例和对照组30例,治疗组采用雷贝拉唑和伊托必利治疗,对照组采用雷尼替丁联合伊托必利治疗,观察比较两组的临床疗效。结果治疗组的有效率为100%,明显高于对照组(75%),两组总有效率比较,差异有统计学意义P<0.01两组的反酸,烧心,胸骨后疼痛的治疗前积分比较,差异无显著性,治疗后,两组的积分均显著低于治疗组P<0.01且治疗组积分与对照组比较,差异也有显著性P<0.01。结论雷贝拉唑联合伊托必利治疗反流性食管炎疗效好,能明显改善临床症状,值得临床推广和应用。
Objective To investigate the clinical efficacy of rabeprazole combined with itopride in the treatment of reflux esophagitis. Methods Sixty-four patients with reflux esophagitis were randomly divided into two groups: treatment group (34 cases) and control group (30 cases). The treatment group was treated with rabeprazole and Itopride, while the control group was treated with ranitidine and Itopride , Observed and compared the clinical efficacy of the two groups. Results The effective rate of the treatment group was 100%, which was significantly higher than that of the control group (75%). The total effective rate of the two groups was statistically significant (P <0.01). The scores of acid reflux, heartburn and post-sternal pain before treatment After treatment, the scores of two groups were significantly lower than those of the treatment group (P <0.01), and the scores of the treatment group were also significantly different from those of the control group (P <0.01). Conclusion Rabeprazole combined with itopride in the treatment of reflux esophagitis has a good curative effect, which can obviously improve the clinical symptoms and is worthy of clinical promotion and application.