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目的研究肝脏局灶性结节性增生(FNH)的临床表现、诊断和治疗。方法对1995~2005年收治的39例FNH患者进行回顾性分析。结果本组患者男性17例,女性22例,年龄21~47岁。主要病史为:慢性腹部隐痛或胀痛14例,发现腹部包块4例,无症状而影像学检查发现肝区占位性病变18例。治疗方法为:手术切除33例,腹腔镜下活检1例,2例细针穿刺病理证实后行微波消融,3例活检后未予以治疗。本组患者随访未见肿物复发。结论本病病程良性经过,预后良好。诊断明确,症状无或者轻微,可以定期随访。手术治疗主要适用于肿物巨大,压迫症状明显,不能排除原发性肝癌或者肝腺瘤的患者。
Objective To study the clinical manifestations, diagnosis and treatment of focal nodular hyperplasia (FNH) in the liver. Methods A retrospective analysis was performed on 39 FNH patients admitted from 1995 to 2005. Results The patients in this group were 17 males and 22 females, aged 21-47 years. The main medical history was as follows: 14 cases of chronic abdominal pain or tenderness, 4 cases of abdominal mass were found, asymptomatic and imaging examination found lesions in the liver area 18 cases. The treatment included 33 cases of surgical resection, 1 case of laparoscopic biopsy, 2 cases of fine needle aspiration biopsy confirmed by microwave ablation and 3 cases of biopsy without treatment. The patients were followed up no recurrence of tumor. Conclusion The course of the disease after benign, the prognosis is good. Diagnosis is clear, no symptoms or mild, you can regular follow-up. Surgical treatment is mainly applied to a huge tumor, compression symptoms were obvious, can not rule out patients with primary liver cancer or liver adenoma.