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34例胃癌患者随机分为两组(每组17例),肠内营养组(enteralnutrition,EN组)和肠外营养组(parenteralnutrinon,PN组)。围手术期给予等热卡等氮量的营养支持,术前进行7~10天的营养支持,术后3~10天经不同途径进行营养支持。结果,术后10天两组血清转铁蛋白(TF)、前白蛋白(Prealb),纤维连接蛋白(FN)水平均显著提高(P<0.05或P<0.01).术后10天PN组Prealb、FN水平显著高于EN组(P<0.31。;而EN组肠功能恢复早于PN组,住院时间和营养费用少于PN组。提示伴有严重营养不良的胃癌患者、围手术期明营养支持能改善机体营养状况;术后短期疗效对比PN优于EN.而EN有利于肠功能恢复.可减少营养费用和住院日。
Thirty-four patients with gastric cancer were randomly divided into two groups (17 in each group), enteral nutrition (EN group) and parenteral nutrition (parenteralnutrinon, PN group). During the perioperative period, nutritional support such as calorific intake of hot calorie, 7 to 10 days of preoperative nutritional support, and 3 to 10 days of postoperative nutrition support by different routes. Results: The levels of serum transferrin (TF), prealb and fibronectin (FN) were significantly increased in the two groups at 10 days postoperatively (P<0.05 or P<0.01). The level of Prealb and FN in PN group was significantly higher than that in EN group at 10 days after operation (P<0.31.) In the EN group, the recovery of bowel function was earlier than that of PN group, and the length of hospital stay and nutrition were less than those in PN group. This suggests that there is severe malnutrition in gastric cancer. Patients and perioperative nutrition support can improve the body’s nutritional status; postoperative short-term efficacy comparison PN is superior to EN. EN is beneficial to intestinal function recovery. It can reduce nutritional costs and hospital stay.