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为进一步了解脑梗死发生的生理生化改变,我们测定了38例脑梗死患者血浆前列环素(PGI2)和血栓素A2(TXA2)的含量及比值,结果表明脑梗死组TXA2水平较对照组显著升高(P<0.05),PGI2水平较对照组显著降低(P<0.05),且TXA2/PGI2明显升高。提示脑梗死患者血小板处于活化状态,内皮细胞功能受损。
To further understand the physiological and biochemical changes of cerebral infarction, we measured the content and ratio of PGI2 and TXA2 in 38 patients with cerebral infarction. The results showed that the level of TXA2 in cerebral infarction group was significantly higher than that in control group (P <0.05). PGI2 level was significantly lower than that of control group (P <0.05), and TXA2 / PGI2 was significantly increased. Tip platelet activation in patients with cerebral infarction, endothelial cell dysfunction.