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目的分析浙江省衢州市2010-2011年手足口病重症病例临床资料和流行特征,以期为重症病例制定合理、有效的防控策略。方法对重症病例进行个案调查并建立数据库,进行回顾性分析。结果 2010年重症病例病情重于2011年,表现在发热、发病-就诊时间、精神差、肢体抖动、脑膜刺激征、WBC升高发生率、平均住院时间等,与2011年相比差异均有统计学意义;流行病学特征无明显差异,分布均以农村为主;男性儿童患病较多,以<5岁儿童为主,尤其是1~2岁组儿童;以散居儿童和幼托儿童为主;发病高峰是4-7月。结论衢州市重症病例感染的病原体仍以EV71为主。通过加强对重点地区人群手足口病防治知识的健康教育,尤其是婴幼儿监护人;大力开展爱国卫生运动,整治周边环境;加强疫情监测;做好患者救治工作,能有效降低重症病例的发生率和死亡率。
Objective To analyze the clinical data and epidemiological characteristics of severe cases of hand-foot-mouth disease in Quzhou City, Zhejiang Province in 2010-2011 so as to formulate a reasonable and effective prevention and control strategy for severe cases. Methods The cases of severe cases were investigated and the database was established for retrospective analysis. Results The prevalence of severe cases in 2010 was heavier in 2011 than in 2011, showing the following factors: fever, morbidity-visit time, mental retardation, limb jitter, meningeal irritation, increased incidence of WBC, average length of stay, etc. There was no significant difference in epidemiological characteristics between the two groups. The distribution of them was mainly in rural areas. Male children were more prevalent, with children less than 5 years old, especially children aged 1-2 years old, Lord; the peak incidence is from April to July. Conclusion The pathogens infected with severe cases in Quzhou are still predominantly EV71. By strengthening the knowledge of hand, foot and mouth disease prevention and control knowledge in key areas of population health education, especially for infants and young children guardians; vigorously carry out patriotic health campaigns, remediation of the surrounding environment; to strengthen epidemiological surveillance; do a good job in patient treatment, can effectively reduce the incidence of severe cases and mortality rate.