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目的:南美学者挽近提出高原红细胞增多症是一个与年龄相关、自然发生的疾病。本文验证这一学说是否符合青藏高原人群,特别世居藏族的发病规律;方法:在海拔3417~4280m间对世居藏族及移居汉族,测定Hb、Hct、静息每分通气量及血气有关指标,求与年龄间的相关关系。自然人群中HAPC症状诊断记分的分布,HAPC的年龄患病率等,综合判定;结果:在世居藏族中Hct、静息通气与年龄间并无明显相关,Hb及HAPC的记分亦未随年龄增长而增高。汉族移居者HAPC的发病年龄高峰在42岁,但从移居高原至发病的间期为22年,故正好重叠在中年期。藏族发病的平均年龄为39.4岁,也处中年期;结论:在青藏高原人群,特别世居藏族,年龄似非发病关键因素
OBJECTIVE: The South American scholars proposed that altitude sickness is an age-related and naturally occurring disease. This study verifies whether this doctrine conforms to the pathogenesis of Tibetan and especially native Tibetans.METHODS: Hb, Hct, resting minute ventilation and blood-gas-related indexes were measured in the living Tibetan and migrant Han from 3417 to 4280m above sea level , Find the correlation between age. The distribution of diagnostic score of HAPC symptom in the natural population and the age of HAPC were determined synthetically. Results: There was no significant correlation between Hct, resting ventilation and age in Habitat Tibetans, nor did Hb and HAPC score increase with age And increased. The peak age of onset of HAPC among Han settlers is at 42 years of age, but it is 22 years from the plateau to the onset of disease, so it coincides with the middle age. The average incidence of Tibetan was 39.4 years old, also in middle-aged; Conclusion: In the Tibetan Plateau, especially the Tibetan, the age is not a key factor in the pathogenesis