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目的:分析小儿中性粒细胞减少症的治疗方法及疗效。方法:将2009年1月～2010年8月收治的小儿中性粒细胞减少症69例患儿随机分为A组(治疗组)35例和B组(对照组)34例。A组除常规应用抗病毒药物及支持治疗外,加用甘露聚糖肽或利可君升白细胞药物治疗;B组常规应用抗病毒药物及支持治疗。比较两组治疗前后的白细胞总数、中性粒细胞绝对值及治愈率。结果:治疗组26例恢复正常,总有效率为74.3%;对照组20例恢复正常,总有效率为58.8%。两组比较P<0.01。结论:小儿粒细胞减少症是严重危害小儿健康的疾病,临床应以预防为主,合理使用抗生素;及早发现并采取针对病因的综合治疗方法可以避免对患儿造成严重损害。
Objective: To analyze the treatment and efficacy of pediatric neutropenia. Methods: A total of 69 children with neutropenia admitted from January 2009 to August 2010 were randomly divided into group A (treatment group), 35 cases, and group B (control group), 34 cases. In addition to routine use of antiviral drugs and supportive therapy, patients in group A were treated with mannan or rifamycin, while those in group B were routinely treated with antiviral drugs and supportive care. The total number of white blood cells, the absolute value of neutrophils and the cure rate of the two groups before and after treatment were compared. Results: The treatment group returned to normal in 26 cases, the total effective rate was 74.3%; control group of 20 patients returned to normal, the total effective rate was 58.8%. The two groups compared P <0.01. CONCLUSIONS: Pediatric neutropenia is a serious disease in children. Clinical should be based on prophylaxis and rational use of antibiotics. Early detection and comprehensive treatment of etiology can avoid serious damage to children.