近日,加拿大一个研究小组在HIV病毒逃避宿主抗病毒免疫应答机制方面取得重要研究进展。他们揭示了HIV病毒是如何利用免疫系统自身“工具”逃避了机体免疫应答并成功入侵宿主的第一道免疫防线。这一突破性发现发表在国际学术期刊plos pathogens上。这项研究的目的在于明确HIV如何在感染初始阶段成功躲避机体的抗病毒免疫应答,这一阶段也叫做急性感染阶段。急性感染阶段是决定病毒感染复杂性,感染程度和艾滋病进展情况的关键阶段,也是在这一阶段,HIV病毒在宿主细胞内建立了长期的储蓄池,这些储蓄池中的病毒 Recently, a research group in Canada made important research progress in the mechanism of the HIV virus evade host anti-viral immune response. They showed how the HIV virus uses the immune system’s own “tools” to evade the body’s immune response and successfully invade the host’s first immunization line. This breakthrough discovery was published in the international academic journal plos pathogens. The purpose of this study was to determine how HIV successfully evolved the body’s anti-viral immune response during the initial stages of infection, a phase called acute infection. The acute phase of infection is a crucial stage in determining the complexity of the virus infection, the extent of infection and the progression of AIDS, and it is also at this stage that the HIV virus establishes long-term pools in the host cell where the virus