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作者报告1例急粒患者并发长期低血钾、尿钾排泄增加达18个月。患者,男,48岁,1974年4月入院。经骨髓检查证实为急粒。入院当时血钾4.3毫当量/升,肌肝廓清率和尿常规正常。数天后血钾下降至3.5毫当量/升。经用先锋霉素、庆大霉素控制感染,血钾持续下降至2.8毫当量/升,此后改为新霉素、粘菌素口服并开始用红比霉素、丙脒腙、阿糖胞苷等化学治疗虽获血液学缓解,血钾仍下降到2.8至1.8毫当量/升,伴有尿钾排泄增多,代谢性碱中毒,肾素和醛固酮增高,同时伴有低钠、低氯、低钙、低尿素血症。4个月后仍低钾及低镁,完全缓解后出院,继续化疗维持治疗,但1974年9月曾因病毒性肝炎第二次入院。1975年1月又因黄疸、腹水、肝功能异常(肝活检疑为酒精性肝硬化)再入院均经治疗恢复出院。同年9月用长春新碱和环磷酰胺治
The authors report that one patient with acute granulomatous complicated by long-term hypokalemia, urinary potassium excretion increased by 18 months. Patient, male, 48 years old, admitted to hospital in April 1974. Confirmed by the bone marrow examination for acute particles. At admission was potassium potassium 4.3 meq / l, clearance rate of muscle liver and urine normal. After a few days the serum potassium dropped to 3.5 meq / l. The use of Pioneer ADM, gentamicin control of infection, serum potassium continued to drop to 2.8 milliequivalents / liter, then replaced by neomycin, colistin orally and started with rubenicillin, propionidrazone, Glycosides and other chemotherapy hematology although relief, blood potassium still dropped to 2.8 to 1.8 milliequivalents / l, accompanied by increased urinary potassium excretion, metabolic alkalosis, renin and aldosterone increased, accompanied by low sodium, low chlorine, Low calcium, low blood urea. 4 months after the low potassium and low magnesium, completely relieved after discharge, continue chemotherapy to maintain treatment, but in 1974 September was due to viral hepatitis second admission. January 1975 because of jaundice, ascites, abnormal liver function (liver biopsy suspected alcoholic cirrhosis) re-admitted after treatment were discharged. In September the same year with vincristine and cyclophosphamide