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目的观察早期应用米力农在重症手足口病治疗中的疗效。方法将皖北煤电集团总医院儿科2013年1月至2014年6月收治的66例重症手足口病患儿随机分为观察组和对照组,对照组为常规治疗,观察组在常规治疗的基础上早期应用米力农辅助治疗,对两组患儿的病情进展、呼吸机应用时间、住院时间、治愈率等资料进行对比分析。比较两组治疗效果。结果对照组9例进展到心肺功能衰竭前期,其中3例并发心肺功能衰竭,死亡1例;观察组4例进展到心肺功能衰竭前期,其中1例并发心肺功能衰竭,无死亡病例。观察组疗效显著优于对照组,差异有统计学意义(P<0.05)。结论重症手足口病尚未进入心肺功能衰竭前期及早应用米力农能有效阻止患儿病情向危重型发展。
Objective To observe the effect of early application of Milrinone in the treatment of severe hand-foot-mouth disease. Methods 66 cases of severe hand-foot-and-mouth disease in our hospital from January 2013 to June 2014 in Wanbei Coal and Electricity Group General Hospital were randomly divided into observation group and control group. The control group was treated routinely. Based on the early application of Milrinone adjuvant therapy, the two groups of children’s disease progression, ventilator application time, hospital stay, cure rates and other data were analyzed. Compare the treatment effect of two groups. Results Nine patients in the control group progressed to the pre-cardiopulmonary failure stage. Three of them were complicated by cardiopulmonary failure and one died. In the observation group, four patients progressed to the pre-cardiopulmonary failure stage, of which 1 was complicated by cardiopulmonary failure without any death. Observation group was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion Severe hand, foot and mouth disease has not yet entered the pre-cardiopulmonary failure early application of Millet can effectively prevent children from developing to critically ill conditions.