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近年来,世界上有许多实验室致力于非甲非乙型肝炎的病原的发现和鉴定,也发展了一些实验诊断技术,但关于病原的本质和疾病的特性至今还处于探索状态。本文复习在这一领城中当前已经清楚和尚未清楚的问题,试图大致反映这一课题的今日状况。一、非甲非乙型肝炎是广泛存在的疾病实体非甲非乙型肝炎是在70年代中期用灵敏的方法筛选HBV感染的输血员后发现的,起初只是在排除已知病毒或其它可认识的病原后,审慎地提出的命名。目前,在输血后肝炎(PTH)中,乙型肝炎只占5～10%,由巨细胞病毒和EB病毒引起的也很少,甲型肝炎几无血液传播,因而90～95%的PTH为非甲非乙型肝炎。另一方面,或许也能说明在健康输血员中此种病毒的感染率很高。
In recent years, there are many laboratories in the world devoted to the discovery and identification of non-A, non-B hepatitis pathogens, and some experimental diagnostic techniques have been developed. However, the nature of the pathogen and the characteristics of the disease are still under exploration. This article reviews issues that are currently clear and unclear in this leading city, and attempt to reflect broadly the current situation on this topic. First, non-A, non-B hepatitis is a widespread disease entity Non-A, non-B hepatitis was discovered in the mid-1970s by a sensitive method of screening for HBV-infected blood transfusions, initially excluding only known viruses or other recognizable After the pathogen, carefully named. At present, in the post-transfusion hepatitis (PTH), only 5 to 10% of hepatitis B, cytomegalovirus and Epstein-Barr virus caused by few, almost no hepatitis A blood transmission, so 90 to 95% of PTH Non-A non-B hepatitis. On the other hand, it may also indicate that the infection rate of such virus is very high among healthy blood transfusion workers.