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目的:探讨rt-PA 50 mg静脉溶栓治疗3 h内急性脑梗死的临床疗效及并发症。方法:2006-01/2008-06对急诊接治发病3 h内的急性脑梗死患者45例给予rt-PA 50 mg静脉溶栓治疗。结果:静脉溶栓再通率64.4%,再通时间(35.2±30.8)min,再闭塞发生率3.5%,轻微出血8.9%,无脑出血现象;溶栓患者4周内有效率77.8%(其中治愈57.8%,显效20.0%),无效11.1%,病死率11.1%。结论:rt-PA 50 mg静脉溶栓治疗3 h内急性脑梗死安全有效,并改善预后。
Objective: To investigate the clinical efficacy and complications of acute cerebral infarction within 3 h after rt-PA 50 mg intravenous thrombolysis. METHODS: From January 2006 to June 2008, 45 patients with acute cerebral infarction within 3 h after emergency treatment were given rt-PA 50 mg intravenous thrombolysis. Results: The recanalization rate was 64.4%, the recurrence time (35.2 ± 30.8) min, the incidence of reocclusion 3.5%, mild bleeding 8.9%, no intracerebral hemorrhage. The effective rate of the thrombolytic therapy within 4 weeks was 77.8% Cured 57.8%, markedly 20.0%), invalid 11.1%, case fatality rate 11.1%. Conclusions: Acute cerebral infarction within 3 h after rt-PA 50 mg intravenous thrombolysis is safe and effective and improves prognosis.