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探讨有临床表现的狼疮性肾炎 (LN)患者与临床、实验室无肾损害证据的系统性红斑狼疮 (SLE)患者肾脏病理改变及临床意义。分别将有临床表现的LN 34例 ,确诊SLE而血、尿检查无肾脏损害的亚临床LN 2 2例进行肾活检 ,观察两组肾脏病理改变。结果示两组肾小球病损率均为 10 0 % ,且WHO分型两组差异亦无显著性 ,肾小管及间质损害两组发生率接近。提示SLE患者早期肾活检确定病理类型 ,及早诊断治疗亚临床LN对肾功能保护的一级预防有重要意义
To investigate the renal pathological changes in patients with systemic lupus nephritis (LN) and clinical and laboratory evidence of renal damage (SLE) and its clinical significance. The clinical manifestations of LN in 34 cases, diagnosed with SLE and blood, urine examination of renal subclinical LN 2 2 cases of renal biopsy, observed two groups of renal pathological changes. The results showed that both groups glomerular lesions were 10%, and the WHO classification was no significant difference between the two groups, tubulointerstitial damage and the incidence of two groups close. Prompt SLE patients with early renal biopsy to determine the pathological type, early diagnosis and treatment of subclinical LN on the primary prevention of renal function is of great significance