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川芎嗪（Ｌｉｇｕｓｔｒａｚｉｎｅ，ＬＩＧ）是从中药川芎中提取分离出来的单体化合物，属弱的钙桔抗剂。在临床上主要用于心血管方面的治疗；在纠正抗药性方面国内外属首次报道。本课题的目的是进一步寻找高效低毒纠正多药抗药性（ Ｍｕｌｔｉｄｒｕｇ ｒｅｓｉｓｔａｎｃｅ
Ligustrazine (LIG) is a monomeric compound extracted from the traditional Chinese medicine Chuanxiong, and it is a weak calcium orange resistant agent. It is mainly used for the treatment of cardiovascular diseases in the clinic; it is the first time that domestic and foreign subjects have been reported to correct drug resistance. The purpose of this topic is to further search for efficient and low toxicity correction of multidrug resistance.