影响出血性转化发生率的因素有溶栓药物(包括种类剂量)及用药时间(开始及持续时间)、年龄,是否有糖尿病、高血压、早期缺血性改变、无症状性微出血灶、脑水肿、脑白质疏松,是否行抗血小板治疗,以及脑梗死病灶的大小和临床症状的轻重等。预测指标分为生化和影像学两方面,可靠性待研究。 Factors that influence the incidence of hemorrhagic transformation include thrombolytic drugs (including the type of dose) and medication time (beginning and duration), age, whether there is diabetes, hypertension, early ischemic changes, asymptomatic micro-hemorrhagic, brain Edema, leukoaraiosis, whether anti-platelet therapy, as well as the size of the infarction and the severity of clinical symptoms and so on. Forecast index is divided into two aspects of biochemistry and imaging, the reliability to be studied.