探讨库兴氏综合征患者高血压的机制是通过体液因素和药理学的测定获得的。其研究结果分别对库兴氏综合征病人的肾素—血管紧张素系统、血管活性、前列腺素和激肽释放酶—激肽系统作出评价。 参与研究的受试者是6名健康的日本人(3名男、3名女,平均年龄31岁)和12名被确诊患有肾上腺肿瘤的库兴氏综合征病人(5名男、7名女,年龄19～65岁)。所有受试者每天摄入氯化钠12g。 The mechanism of Hypertension in patients with Cushing’s syndrome is obtained through the measurement of humoral factors and pharmacology. The results of this study evaluated renin-angiotensin system, vasoactive, prostaglandin, and kallikrein-kinin systems in patients with Cushing’s syndrome. Participants in the study were 6 healthy Japanese (3 males and 3 females, mean age 31 years) and 12 Cushing’s syndrome patients diagnosed with adrenal tumors (5 males and 7 females Female, age 19 ~ 65 years old). All subjects daily intake of sodium chloride 12g.