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目的探讨无创呼吸机在慢阻肺合并急性呼吸衰竭患者临床治疗中的应用效果。方法选择2014年3月-2015年12月医院收治的慢阻肺合并急性呼吸衰竭的老年患者90例。随机分为观察组和对照组各45例,对照组给予常规治疗,观察组应用无创呼吸机正压通气治疗,观察2组治疗2h后血气指标、临床效果、有创通气率及病死率等。结果治疗2h后观察组p H值为(7.3±0.2)、Pa CO2(68.5±1.9)mm Hg明显低于对照组的(7.4±0.2)、(72.5±1.2),而Pa O2为(65.8±2.9)mm Hg明显高于对照组的(58.6±1.9)mm Hg,差异有统计学意义(P<0.05)。观察组有创通气率、病死率明显低于对照组、观察组总有效率为82.22%明显高于对照组的62.22%,差异有统计学意义(P<0.05)。结论无创呼吸机辅助通气有助于提高慢阻肺合并急性呼吸机衰竭患者的治疗效果,且经济简便,值得推广使用。
Objective To investigate the effect of noninvasive ventilator in clinical treatment of COPD patients with acute respiratory failure. Methods 90 elderly patients with chronic obstructive pulmonary disease and acute respiratory failure admitted from March 2014 to December 2015 in our hospital were selected. Randomly divided into observation group and control group of 45 cases, the control group given conventional treatment, the observation group with noninvasive ventilator positive pressure ventilation treatment, 2 hours after treatment observed blood gas index, clinical effect, invasive ventilation rate and mortality and so on. Results The p H value in the observation group was (7.3 ± 0.2) and PaCO 2 (68.5 ± 1.9) mm Hg was significantly lower than that in the control group (7.4 ± 0.2) and (72.5 ± 1.2) 2.9) mm Hg was significantly higher than that of the control group (58.6 ± 1.9) mm Hg, the difference was statistically significant (P <0.05). The invasive ventilation rate and mortality in the observation group were significantly lower than those in the control group. The total effective rate in the observation group was 82.22%, which was significantly higher than that in the control group (62.22%, P <0.05). Conclusion Noninvasive ventilator-assisted ventilation helps to improve the curative effect of COPD patients with acute respiratory failure, and it is economical and simple and should be widely used.