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本研究用中国原子能科学院物理研究所的HI13串列加速器产生的Li(Z=3,LET=100keV/μm)离子束以0.5-6.0Gy剂量照射人支气管上皮细胞系(BEAS-2B),来观察重离子辐射诱发的细胞染色体畸变。分析经Li离子照射细胞的染色体,除了如同对照组那样的发现5号、15号、22号的X染色体丢失、出现4条标记染色体及染色体数目仍以46条为主以外,在早期细胞中有非稳定性畸变,对照组细胞丢失的21号染色体重新出现以及X染色体丢失
In this study, Li (Z = 3, LET = 100keV / μm) ion beam generated by the HI13 tandem accelerator at Institute of Physics, Chinese Academy of Atomic Energy was used to irradiate human bronchial epithelial cell line (BEAS- 2B) to observe the chromosomal aberrations induced by heavy ion radiation. Analysis of chromosomes irradiated by Li ion showed that in addition to the control group, the X chromosome was found missing on the 5th, the 15th and the 22nd, and the number of the four labeled chromosomes and the number of the chromosomes remained at 46. In the early cells Unstable distortions, reappearance of chromosome 21 loss in control cells, and loss of X chromosome