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随着原子能和平利用的日益广泛,辐照食品保鲜在世界各国蓬勃发展。但辐照食品是否有诱变活力,人畜食用是否有潜在的遗传危险,是人们关注的问题。过去对定期检查潜在性遗传危险的测定,是观察分析细胞分裂中期染色体畸变,但此法费时,步骤繁琐,分析细胞工作量甚大。近年来,一些遗传实验室、放射生物学实验室均利用哺乳动物骨髓细胞微核的出现率来初测各种可能具有诱发染色体畸变潜力的物质。我们的试验是用辐射蘑菇喂饲大白鼠来测定辐射蘑菇对大白鼠骨髓晚幼红细胞微核率的影响。
With the ever-widening utilization of atomic energy, the preservation of irradiated food has been booming in all countries of the world. However, whether irradiated foods have mutagenic activity or whether human and animal consumption have potential genetic hazards is a matter of concern. In the past, the determination of the potential genetic risk at regular intervals was to observe and analyze metaphase chromosome aberrations. However, this method is time-consuming and cumbersome, and the analysis of cell workload is very large. In recent years, some genetic laboratories and radiobiology laboratories have used the frequency of micronuclei in mammalian bone marrow cells to initially measure various substances that may have the potential to induce chromosomal aberrations. Our experiment was to measure the effect of irradiated mushrooms on the micronuclear rate of rat erythrocytes in the bone marrow of irradiated rats by irradiation of mushroom-fed rats.