铁蛋白(Ferritin 简称Ft)是一种分子量较大的含铁蛋白质,能溶解扩散,是铁的主要贮存形式之一。自1937年Laufberger分离出这种含铁蛋白质以来,人们对其结构、理化性质、代谢及临床意义进行了大量地研究。特别是近几年来,关于血清铁蛋白(简称SF)与贫血、肿瘤的关系;红细胞内Ft 与贫血;Ft 的实验室检测等方面取得了较大进展。铁蛋白分子结构及分布〔分子结构〕Ft 有一球性蛋白质外壳,直径12～14nm,厚3～4nm,内包有一个核,核直径为6.4～6.5nm。电镜下,Ft Ferritin (Ferritin referred to as Ft) is a high molecular weight iron-containing protein, can dissolve and spread, is one of the main storage form of iron. Since the separation of this iron-containing protein by Laufberger in 1937, there has been extensive research into its structure, physicochemical properties, metabolism and clinical significance. Especially in recent years, great progress has been made on the relationship between serum ferritin (referred to as SF) and anemia and tumor, Ft and anemia in erythrocytes, and laboratory testing of Ft. Ferritin Molecular Structure and Distribution [Molecular Structure] Ft has a globular protein shell with a diameter of 12 to 14 nm and a thickness of 3 to 4 nm, containing a core with a core diameter of 6.4 to 6.5 nm. Under electron microscope, Ft