论文部分内容阅读
目的 :探讨人乳头瘤病毒 (HPV)感染与置宫内节育器 (IUD)后出血之间的关系。方法 :应用 HPV6、1 1型和 HPV1 6、1 8型两对引物 ,通过聚合酶链反应 (PCR)技术 ,对放置 IUD出血病例、放置 IUD无出血病例、未放置 IUD正常妇女和未放置 IUD子宫异常出血病例进行 HPV-DNA检测。结果 :置 IUD出血组 HPV阳性率 (52 .9% )显著置 IUD正常组 (2 1 .7% )和未置 IUD正常组 (1 3.3% ) ;而与未置 IUD子宫异常出血组无差异 (40 .0 % )。置 T型 IUD者 HPV阳性率显著高于置 O型 IUD及未置 IUD者 ;置 IUD出血组中 ,置 T型 IUD者 HPV阳性率显著高于置 O型IUD者。结论 :置 IUD后出血与 HPV感染有关。
Objective: To investigate the relationship between human papillomavirus (HPV) infection and hemorrhage after intrauterine device implantation (IUD). Methods: Two pairs of primers of HPV type 6,1 1 and type HPV 1 6,1 8 were used to detect the bleeding of IUD by polymerase chain reaction (PCR). The bleeding cases of IUD, the normal women without IUD, the normal women without IUD, Uterine abnormalities in cases of HPV-DNA testing. Results: The positive rate of HPV in IUD group (52.9%) was significantly higher than that in normal IUD group (21.7%) and normal IUD group (3.3%), but no difference with uterine bleeding group without IUD (40.0%). The positive rate of HPV in T type IUD patients was significantly higher than that in type I IUDs and no type IUDs. The positive rate of HPV in T type IUDs was significantly higher in type IUD patients than in type I type IUDs. Conclusion: Bleeding after IUD implantation is associated with HPV infection.