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目的:探讨腹腔镜联合药物治疗子宫内膜异位症的临床疗效。方法:采用腹腔镜联合药物的方法进行治疗。结果:在80例子宫内膜异位症患者中共失访4例,失访率5.00%(4/80)(其中孕三烯酮组失访1例,GnRH-α组失访2例,对照组失访1例)。在随访的26例孕三烯酮组子宫内膜异位症患者中有效15例,基本有效10例,无效1例,复发1例;25例Gn-RH-α组子宫内膜异位症患者中有效21例,基本有效3例,无效1例,复发1例;与对照组相比,腹腔镜与药物联合治疗的孕三烯酮组和GnRH-α组的有效率明显高于对照组(P<0.05);而GnRH-α组的有效率明显高于孕三烯酮组(P<0.05);结论:腹腔镜手术联合GnRH-α治疗子宫内膜异位症,可以降低疾病复发率,提高患者受孕率,是一种有效的临床治疗方法,值得临床推广使用。
Objective: To investigate the clinical efficacy of laparoscopy combined with drug treatment of endometriosis. Methods: The method of laparoscopy combined with drugs for treatment. Results: Of the 80 patients with endometriosis, 4 were lost to follow-up, with a rate of 5.00% (4/80) of follow-up (Gus Rexone group lost one case, GnRH-α group lost two cases, Group lost one case). In the follow-up of 26 cases of gestrinone group, endometriosis was effective in 15 cases, 10 cases were basically effective, 1 case was ineffective, and 1 case relapsed; 25 cases of Gn-RH-α group had endometriosis Effective in 21 cases, basically effective in 3 cases, ineffective in 1 case and recurrent in 1 case. Compared with the control group, the effective rate of gestrinone and GnRH-α group was significantly higher than that of the control group (P <0.05). The effective rate of GnRH-α group was significantly higher than that of gestrinone (P <0.05). Conclusion: Laparoscopic surgery combined with GnRH-α for endometriosis can reduce the disease recurrence rate, Improve the rate of patients with conception, is an effective clinical treatment, it is worth to promote clinical use.