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多发性硬化(MS)是中枢神经系统(CNS)的一种广泛脱髓鞘性自身免疫疾病。目前认为是一种CD4+的Th1细胞为主的细胞免疫疾病。Th1/Th2细胞平衡在其发病过程中起到重要的作用。寄生虫感染(特别是血吸虫虫卵)可引起Th1/Th2平衡的偏移,对MS有潜在的治疗意义,引起人们对此的兴趣。
Multiple sclerosis (MS) is a widespread demyelinating autoimmune disease of the central nervous system (CNS). Currently considered a CD4 + Th1 cell-based cellular immune disease. Th1 / Th2 cell balance plays an important role in its pathogenesis. Parasitic infections (especially Schistosoma japonicum eggs) can cause a shift in the Th1 / Th2 balance, potentially therapeutic for MS, arousing people’s interest in this.