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目的探讨胸腺瘤合并重症肌无力的外科治疗经验。方法回顾分析我科2006年10月至2011年12月手术治疗的60例胸腺瘤合并重症肌无力患者的的临床资料,分析其临床特点、手术原则及手术疗效等。结果本组60例患者,围手术期死亡1例。随访6月～3年,有效45例(75%),好转11例(18.3%),无效2例(3.3%),恶化2例(3.3%)。结论手术治疗胸腺瘤合并重症肌无力可获良好疗效。准确把握手术时机,加强围手术期管理,手术彻底切除肿瘤,是提高疗效、降低术后并发症及病死率的关键。
Objective To investigate the surgical treatment of thymoma with myasthenia gravis. Methods The clinical data of 60 patients with myasthenia gravis combined with myasthenia gravis treated surgically from October 2006 to December 2011 in our department were retrospectively analyzed. The clinical features, surgical principles and surgical outcomes were analyzed. Results 60 patients in this group, perioperative death in 1 case. Follow-up ranged from 6 months to 3 years, 45 (75%) were effective, 11 (18.3%) were improved, 2 (3.3%) were ineffective and 2 (3.3%) were exacerbated. Conclusion Surgical treatment of thymoma with myasthenia gravis has a good effect. Accurately grasp the timing of surgery to enhance perioperative management, complete removal of the tumor surgery is to improve the efficacy and reduce postoperative complications and mortality is the key.