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目的 :探讨经门静脉用药途径丹参对肝硬变肝纤维化指标的影响。方法 :将 30例肝炎后肝硬变患者治疗前后用放射免疫法测定血清透明质酸 (HA)、 型前胶原 (Pc )、 型胶原蛋白 (C )、层粘蛋白 (L N )水平。结果 :治疗后 HA、Pc 、C 、L N水平与治疗前比较 ,有极显著性差异 (P <0 .0 1)。结论 :经门静脉用药途径丹参对肝硬变肝纤维化指标有较大的改善
Objective: To investigate the effect of Salvia miltiorrhizae via portal vein on hepatic fibrosis index. Methods: Serum hyaluronic acid (HA), procollagen (PC), collagen (C) and laminin (L N) levels were measured by radioimmunoassay in 30 patients with posthepatitic cirrhosis before and after treatment. Results: The levels of HA, Pc, C and L N after treatment were significantly different from those before treatment (P <0.01). Conclusion: Salvia miltiorrhiza through portal vein has a great improvement on liver cirrhosis index