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目的研究苏合香包合物的药理作用。方法观察苏合香包合物对乙醇及亚硝酸钠致小鼠记忆障碍模型的影响;采用注射冰醋酸制造小鼠疼痛模型,观察苏合香包合物的镇痛作用;观察苏合香包合物对戊巴比妥钠致小鼠睡眠的影响作用。结果苏合香包合物能显著降低乙醇及亚硝酸钠致小鼠记忆障碍平均潜伏期;对化学刺激引起的疼痛有一定的镇痛作用;能显著延长戊巴比妥钠所致小鼠的睡眠潜伏期和缩短睡眠持续时间。结论苏合香包合物具有一定的改善小鼠记忆障碍、镇痛、催醒作用。
Objective To study the pharmacological effects of Su-He-Xiang inclusion compound. Methods To observe the effect of Suhexiang inclusion compound on the model of memory impairment caused by ethanol and sodium nitrite in mice. The mice model of pain was made by injection of glacial acetic acid to observe the analgesic effect of Suhexiang inclusion compound. Effect of sodium on sleep in mice. Results Suhexiang inclusion compound can significantly reduce the average latency of mice with memory impairment caused by ethanol and sodium nitrite; have some analgesic effect on the pain caused by chemical stimulation; can significantly prolong the sleep latency of mice induced by pentobarbital sodium and Shorten the sleep duration. Conclusion Su-He-Xiang inclusion compound can improve memory impairment, analgesia and reminding effect in mice.