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一、前言目前治疗血吸虫病的药物,虽以酒石酸锑钾最为有效,但此药物毒性较大,病人用后常有不适之感,其他如卜缶糖酸锑铵毒性很小而疗效不太显著、又不稳定、不能煮沸灭菌,为此,我们想寻找一种制造方便、毒性又小、且对血吸虫病有治疗效果的药物。根据蔗糖的性质,它能与铁钙等氢氧化物相结合,据Nissim的研究,含糖铁制剂的毒性小于卜缶糖酸铁可供静脉注射,卜缶糖有解毒作用,与酒石酸锑钾同用能显著地降低毒性,同时,锑既可与卜缶糖酸在硷性溶液中结合成卜缶糖酸锑鈵,或卜缶糖酸锑铵,且可能与廿
I. Preface The current treatment of schistosomiasis drugs, although the most effective antimony potassium tartrate, but the drug toxicity, the patient often have the feeling of discomfort, the other such as Bu Xi antimony ammonium bicarbonate toxicity is small and the effect is not significant , But also unstable and can not be boiled for sterilization. Therefore, we want to find a drug that is easy to manufacture, less toxic and has a therapeutic effect on schistosomiasis. According to the nature of sucrose, it can combine with calcium hydroxide and other hydroxides. According to the research of Nissim, the toxicity of the sugar-containing iron preparation is less than that of the sodium brorate, which is available for intravenous injection. The sugar of the cauliflower is detoxified, With the use of can significantly reduce the toxicity, at the same time, antimony with both Bu sugar acid in alkaline solution into the combination of Bu 缶 sugar acid antimony 卜, or Bu 缶 antimony ammonium borate, and may be 20