锰作为机体细胞线粒体中许多抗氧化物酶如谷胱甘肽、超氧化物岐化酶等重要的组成成份和许多酶的激动剂,对多种器官功能活动发挥着重要作用。已有资料表明,过量的锰既可透过血脑屏障损害锥体外系结构,导致类帕金森氏征[1-2];又可对肝脏[3]、心血管[4]和免疫系统[5]等造成不同程 Manganese, as an important component of many mitochondrial mitochondrial antioxidant enzymes such as glutathione and superoxide dismutase and many other enzyme activators, plays an important role in various organ function activities. It has been shown that excess manganese can damage the extrapyramidal structure through the blood-brain barrier, leading to Parkinson’s syndrome [1-2], but also to the liver [3], cardiovascular [4] and immune system [ 5], etc. caused by different procedures