呼气末正压(PEEP)机械通气是一种公认的治疗急性呼吸衰竭的疗法。为了维持这些病人的氧供,需进行一段时间的PEEP,但PEEP可增高胸腔内压,影响心脏回血和降低心输出量,但PEEP对眼内压的影响尚不明确。眼内压急剧升高可影响视神经视头的灌注,引起视神经视头缺血和不可逆性萎缩,因此测定PEEP对眼内压的影响非常重要。 Positive end-expiratory pressure (PEEP) Mechanical ventilation is a well-accepted therapy for acute respiratory failure. In order to maintain oxygen supply to these patients, PEEP is required for a period of time, but PEEP can increase intrathoracic pressure, affect cardiac blood flow and reduce cardiac output, but the effect of PEEP on intraocular pressure is not yet known. Rapid intraocular pressure can affect the perfusion of optic nerve head, causing optic nerve head ischemia and irreversible atrophy, so the determination of intraocular pressure on the impact of PEEP is very important.