患儿男,2个月,以支气管肺炎收入院。患儿系第二胎,第一产,足月顺产。出生体重为2500g,生后窒息5分钟。父母年龄均为29岁,母孕期无传染病、放射线和有毒物质接触史及服药史,家族中无类似的疾病。父母发育及智力无异常,非近亲结婚。体检:身长52cm,体重3400g,发育、营养差。哭声低如猫叫,呼吸急促,口唇轻度发绀,三凹征明显。小头畸形,头围34cm,满月脸,眼距宽,眼裂小,斜视,有内 Children male, 2 months to bronchial pneumonia income hospital. Children with a second child, the first birth, term full-term. Birth weight of 2500g, 5 minutes after birth asphyxia. Both parents were 29 years old. There was no infectious disease during the first trimester, the history of exposure to radiation and toxicants and medication history, and no similar disease in the family. Parents and no abnormal intelligence development, non-relatives get married. Physical examination: length 52cm, weight 3400g, development, poor nutrition. Cries low as cats, shortness of breath, lips mild cyanosis, three concave sign obvious. Small head deformity, head circumference 34cm, full moon face, wide eyes, small cleft, strabismus, there are