氯麻滴鼻剂是氯霉素与盐酸麻黄碱组成的复方制剂。对盐酸麻黄碱的含量制剂手册甩银量法来测定,此法终点不易掌握、误差较大。本文依据酸性染料比色法的原理,对本制剂中的主要成分盐酸麻黄碱进行了含量测定,此法简便易行、结果满意。1 仪器与药品721分光光度计(上海光字仪器厂);0.1%溴麝香章酚蓝溶液;邻苯二甲酸氢钾缓冲液(取邻苯二甲酸氢钾4g,加500ml 蒸 The chloramphenicol nasal drops are compound preparations composed of chloramphenicol and ephedrine hydrochloride. The determination of the content of ephedrine hydrochloride in the formulation manual is determined by the silver throwing method. The end point of this method is not easy to grasp and the error is large. Based on the principle of acid dye colorimetry, the content of ephedrine hydrochloride, the main component of this preparation, was determined. This method is simple, and the results are satisfactory. 1 Instruments and Drugs 721 spectrophotometer (Shanghai Optoelectronic Instrument Factory); 0.1% Bromogermanium phenol blue solution; potassium hydrogen phthalate buffer (take potassium hydrogen phthalate 4g, plus 500ml steam