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第三、四代喹诺酮类药物以其广谱、抗菌作用强、组织分布广、生物利用度高等特点,被临床广泛应用。在同时伴有病毒感染的病例,常联用抗病毒中药注射液。近来我院在使用环丙沙星注射液序贯穿琥宁注射液时有混浊、沉淀的现象,此类配伍未见报道。为此我们选择了抗病毒中药一穿琥宁和鱼腥草注射液,分别与5种喹诺酮注射液做交叉配伍试验,在一定时间内观察其混合液的外观、pH及微粒变化,为临床合理配伍提供依据。1 仪器与药品1.1 仪器pHs-3CJING精密PH计（上海雷磁仪器厂）;注射液微粒分析仪ZWF-413（空军天津医疗仪器
The third and fourth generation quinolones are widely used clinically because of their broad spectrum, strong antibacterial effect, wide distribution of tissues and high bioavailability. At the same time accompanied by a virus infection in cases, often with antiviral traditional Chinese medicine injection. Recently, our hospital in the use of ciprofloxacin injection sequential Chuanhuning injection when the phenomenon of turbidity, precipitation, such compatibility has not been reported. To this end, we have selected an antiviral Chinese medicine chuanhunun and Houttuynia injection, respectively, with five quinolone injection cross compatibility test, in a certain period of time to observe the appearance of the mixture, pH and particle changes for the clinical reasonable compatibility provided in accordance with. 1 instruments and pharmaceuticals 1.1 instruments pHs-3CJING precision PH meter (Shanghai Lei Magnetic Instrument Factory); injection particle analyzer ZWF-413 (Air Force Tianjin Medical Instruments