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目的:观察蚓激酶对急性脑梗塞的疗效。方法:将74例急性脑梗塞患者随机分为两组,治疗组39例,采用蚓激酶+血塞通治疗。对照组35例,采用阿斯匹林+血塞通治疗。用临床神经功能缺损评分对两组病人进行评定并进行t检验。结果:治疗后治疗组神经缺损评分明显减少,与对照组相比p<0.001全血粘度、血浆粘度、纤维蛋白原及血小板聚集率均明显降低,与治疗前相比均p<0.001结论:蚓激酶对急性脑梗塞疗效显著;能明显降低全血粘度、血浆粘度、纤维蛋白原及血小板聚集率;且无明显的毒副作用。
Objective: To observe the effect of lumbrokinase on acute cerebral infarction. Methods: A total of 74 acute cerebral infarction patients were randomly divided into two groups. The treatment group (39 cases) was treated with lumbrokinase and Xuesaitong. The control group of 35 cases, the use of aspirin + Xuesaitong treatment. Clinical neurological deficit scores were used to assess both groups and t test. Results: After treatment, the score of neurological deficit in treatment group decreased significantly, p <0.001 compared with the control group, the whole blood viscosity, plasma viscosity, fibrinogen and platelet aggregation rate were significantly lower than those before treatment, p <0.001 Conclusion: The effect of kinases on acute cerebral infarction was significant; the whole blood viscosity, plasma viscosity, fibrinogen and platelet aggregation rate were significantly reduced; and no obvious side effects.