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目的 探讨阿奇霉素在治疗肺炎支原体感染的疗效。方法 选择 77例支原体感染患儿随机分为阿奇霉素组 41例 ,红霉素组 36例 ,观察患儿症状、体征及实验室、X线检查及不良反应情况。结果 阿奇霉素组 41例中 ,显效 2 5例 ,有效12例 ,红霉素组 36例中 32例完成治疗 ,显效 16例 ,有效 13例 ,总有效率分别为 92 6 8%、90 6 3% ,经统计处理无显著差异。不良反应发生率分别为 9 76 %、47 2 2 % ,经统计处理有显著差异。结论 阿奇霉素治疗肺炎支原体感染在用药时间、途径 ,不良反应方面优于红霉素 ,疗效和红霉素无差异
Objective To investigate the efficacy of azithromycin in the treatment of Mycoplasma pneumoniae infection. Methods Totally 77 children with mycoplasma infection were randomly divided into azithromycin group (n = 41) and erythromycin group (n = 36). The symptoms, signs, laboratory and X-ray examination and adverse reactions in children were observed. Results Among 41 cases of azithromycin group, 25 cases were effective and 12 cases were effective. Among 36 cases of erythromycin group, 32 cases completed treatment, 16 cases were markedly effective and 13 cases were effective. The total effective rates were 92.68% and 90.63% , No significant difference after statistical processing. The incidence of adverse reactions were 9 76% and 47 2 2%, respectively, with significant differences after statistical treatment. Conclusion Azithromycin treatment of Mycoplasma pneumoniae infection in the time, route, adverse reactions than erythromycin, no difference in efficacy and erythromycin