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目的探讨三联(复方丹参注射液、654-2和硝普钠)对ARDS的作用。方法19例ARDS病人被分为甲组和乙组,在呼吸支持和常规治疗的同时,甲组输注硝普钠;乙组输注三联(复方丹参注射液、654-2和硝普钠),直至具备呼吸机脱离指征。结果乙组病人的氧合和部分呼吸动力参数都有明显改善,末梢循环状况良好。结论三联能降低肺血管和全身血管阻力,减轻心脏负荷,改善微循环和组织灌注,减少炎性调理介质释放,有利于改善ARDS病人肺功能和全身性病理生理改变。
Objective To investigate the effect of triple combined (Salvia miltiorrhiza injection, 654-2 and sodium nitroprusside) on ARDS. Methods Nineteen patients with ARDS were divided into two groups: group A and group B, while sodium nitroprusside was given to group A while respiratory support and routine treatment were given. Group B received triple infusion of compound salvia miltiorrhiza (654-2 and sodium nitroprusside) Until you have a ventilator out of indications. Results Patients in group B had significantly improved oxygenation and partial respiratory parameters, and peripheral circulation was good. Conclusion Triple can reduce pulmonary vascular and systemic vascular resistance, reduce cardiac load, improve microcirculation and tissue perfusion, reduce the release of inflammatory mediators, is conducive to improving lung function and systemic pathophysiology of ARDS patients.