论文部分内容阅读
1991年元月～1995年2月我们治疗晚期鼻咽癌患者160例,随机分为两组进行对照,A组:新辅助化疗+放射治疗;B组:单纯放射治疗。结果表明:A组治疗后及治疗后6月鼻咽部肿瘤消退率各为89.71％、96.15％,B组为73.33％、86.67％;颈淋巴结消退率A组放疗后,疗后6个月各为87.18％、92.31％,B组分别为72.00％、80％。A和B组消退率均有显著差异(P<0.05)。1年复发和/或转移率A组为16.67％,B组为30.67％。两者差异显著(P<0.05)。作者认为晚期鼻咽癌放疗前给予新辅助化疗,可以提高疗效并且可控制局部复发和远处转移。
From January 1991 to February 1995, we treated 160 patients with advanced nasopharyngeal carcinoma and were randomly divided into two groups for control. Group A: neoadjuvant chemotherapy plus radiation; Group B: Radiotherapy alone. The results showed that the regression rates of nasopharyngeal tumor in group A after treatment and in June were 89.71% and 96.15% respectively, in group B were 73.33% and 86.67%, respectively. The regression rate of cervical lymph node in group A was 6 months after radiotherapy 87.18% and 92.31% respectively, while those in group B were 72.00% and 80% respectively. There were significant differences in the regression rates between groups A and B (P <0.05). One-year recurrence and / or metastasis rates were 16.67% in group A and 30.67% in group B. The difference was significant (P <0.05). The authors believe that neoadjuvant chemotherapy before radiotherapy for advanced nasopharyngeal carcinoma can improve the efficacy and can control local recurrence and distant metastasis.