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目的:对湖州市中心医院骨科住院病人围术期抗菌药物的合理使用情况进行评价分析,为加强临床合理安全用药提供依据。方法:采用回顾性分析的方法,对2011年2月~2013年12月入住湖州市中心医院骨科进行治疗的293例患者的围术期抗菌药物用药资料进行统计分析。结果:293例患者,全部使用过抗菌药物,使用率为100%,使用频率由高到低依次为头孢菌素类(96.93%)、青霉素类(92.49%)、氨基糖甙类(36.18%)、大环内酯类(4.78%)、其他(1.71%),使用时间分别为(8.05±1.61)天、(1.79±0.32)天、(5.46±1.25)天、(3.97±0.84)天、(5.28±1.58)天。单用168例(57.34%),二联109例(37.20%),多联16例(5.46%),使用时间分别为(8.73±2.56)天、(5.56±1.74)天、(3.15±0.82)天。结论:湖州市中心医院骨科住院病人围术期抗菌药物的使用基本合理,针对存在的一些问题,采取措施,加强抗菌药物的合理应用,能够有效控制感染,促进患者康复,同时减轻患者经济负担。
Objective: To evaluate and analyze the rational use of perioperative antibiotics in the orthopedics inpatients of Central Hospital of Huzhou City to provide the basis for strengthening the rational and safe use of drugs. Methods: A retrospective analysis was performed to analyze the data of perioperative antibacterial drug use in 293 patients who were admitted to Huzhou Central Hospital from February 2011 to December 2013. Results: All the 293 patients were treated with antimicrobial agents, with 100% use rate. The order of use was cephalosporins (96.93%), penicillins (92.49%) and aminoglycosides (36.18%), (4.79 ± 0.32) days, (5.46 ± 1.25) days, (3.97 ± 0.84) days, and (3.97 ± 0.84) days respectively for the macrolides (4.78% 5.28 ± 1.58) days. (8.73 ± 2.56) days, (5.56 ± 1.74) days and (3.15 ± 0.82) days respectively in 168 patients (57.34%), 109 patients (37.20%) and 16 patients (5.46% day. Conclusion: The use of perioperative antibacterials in patients in orthopedics department of Huzhou Central Hospital is reasonable. According to some existing problems, some measures should be taken to strengthen the rational use of antibacterials, which can effectively control the infection and promote the recovery of patients, at the same time reduce the economic burden of patients.