采用随机抽样方式调查了武汉市　口区６４８名１８～６５岁妇女的雀斑、黄褐斑的发病情况。调查了患者年龄、日晒、妊娠、避孕药使用、家族遗传等八大因素与发病间的关系，对调查结果进行了分类整理，并作了相应的统计学处理。认为影响雀斑发生的主要因素为相应年龄，日晒程度；其次为避孕药及妊娠等，年龄、避孕药、妊娠又与雌激素、孕激素在体内的含量有关。 A random sample was used to investigate the incidence of freckles and chloasma in 648 women aged 18 ~ 65 years in Wuhan. The relationship between the eight factors such as patient’s age, sun, pregnancy, use of contraceptives and family heredity was investigated. The survey results were classified and sorted out, and the corresponding statistical analysis was made. The main factors that affect the occurrence of freckles that the corresponding age, degree of sun; followed by contraceptives and pregnancy, age, contraceptives, pregnancy and estrogen and progesterone in vivo content.