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目的探讨老年脑梗死对认知和执行功能的影响。方法设140例腔隙性脑梗死患者和38例老年对照组,两组患者分别进行认知和执行功能测验。腔隙性脑梗死中,顶叶卒中24例(17.1%),额叶卒中22例(15.7%),颞叶卒中11例(7.8%),丘脑卒中20例(14.3%),基底节卒中45例(32.1%),小脑卒中14例(10.0%),桥脑卒中14例(10.0%)。结果与对照组比较,腔隙性脑梗死组的MMSE、stroop色词测验、画钟测验和语言流畅性测验评分差异有统计学意义(P<0.05)。结论老年腔隙性脑梗死患者存在一定的执行功能减退。提示老年不同部位腔隙性脑梗死均对执行功能产生影响,尤以额叶和基底节区脑梗死为甚,对老年腔隙性脑梗死患者的预后判断和综合治疗提供参考。
Objective To investigate the effect of senile cerebral infarction on cognitive and executive functions. Methods A total of 140 patients with lacunar infarction and 38 elderly controls were enrolled. Patients in both groups were assessed for cognitive and executive function. Among lacunar infarcts, 24 (17.1%) had parietal stroke, 22 (15.7%) had frontal stroke, 11 (7.8%) had temporal lobe stroke, 20 (14.3%) had thalamic stroke, Cases (32.1%), stroke in 14 cases (10.0%), stroke in 14 cases (10.0%). Results Compared with the control group, there were significant differences in MMSE, stroop color word test, draw-bell test and verbal fluency test score in lacunar infarction group (P <0.05). Conclusion Elderly patients with lacunar infarction have some executive dysfunction. It is suggested that lacunar infarction in different parts of the elderly has an impact on the executive function, especially in frontal lobe and basal ganglia infarction. It provides a reference for the prognosis and comprehensive treatment of elderly patients with lacunar infarction.